Procaine Hydrochloride Local Anesthetic Powder For Infiltrating Local Anesthesia

 
Procaine Hydrochloride Local Anesthetic Powder For Infiltrating Local Anesthesia
 
Quick details
 
Procaine hydrochloride / Procaine HCL
CAS No.: 51-05-8
Molecular formula: C13H21ClN2O2
Molecular weight: 272.77
Melting point 155-156 °C (lit.)
Boiling point 195-196°C 17mm
Storage condition room temp
Uses Local anesthetics for invasive local anesthesia, nerve block, etc.
 
 
 
What is procaine hydrochloride?
 
Procaine hydrochloride, also known as Novocain. It is a local anesthetic that temporarily blocks the conduction of nerve fibers.
 
It has an anesthetic effect, strong action, low toxicity, no addiction, but weak penetration of skin and mucous membranes. Not suitable for topical anesthesia, patients for infiltration, spinal and conduction anesthesia.
 
 
 
What is the use of procaine hydrochloride?
Procaine is a local anesthetic. Procaine causes loss of sensation in the skin and mucous membranes (numbness). Procaine is used as an injection during surgery and other medical and dental procedures. Procaine can also be used for purposes other than those listed here.
 
 
 
Is procaine the same as lidocaine?
Prokamide and mepivacaine have been studied, but only procaine is currently approved for spinal anesthesia in the United States. Current research indicates that procaine produces spinal cord anesthesia with the same duration and sensory level as lidocaine, and suggests that it is less likely to cause TNS.
 
 
 
What is the work of procaine?
Procaine benzyl penicillin, also known as penicillin G procaine, is an antibiotic that can be used to treat a variety of bacterial infections.
 
Specifically, it is used for syphilis, anthrax, oral infections, pneumonia, diphtheria, cellulitis and animal bites. It is given by injection into the muscles.
 

 
Procaine and lidocaine for spinal anesthesia: a random comparison of the incidence of transient neurological symptoms
 
method:
A commercial spinal solution of 10% procaine or high pressure 5% lidocaine was diluted 1:1 with CSF prior to injection.
 
For procedures expected to require 45-90 minutes, first add 20 mcg (0.4 ml) of fentanyl and then add CSF sufficient to reduce the final concentration to 2.5% lidocaine or 5% procaine.
 
The dose of lidocaine (40 or 50 mg) or procaine (60, 80 or 100 mg) is selected by an unblinded anesthesiologist who is undergoing spinal treatment to achieve approximately the desired level of sensation.
 
 
 
RESULTS:
 
TNS was not present in patients with procaine, and 4 (5.7%) were patients with lidocaine, but were not statistically significant (p = .056).
 
The mean maximum sensory level of procaine and lidocaine and the duration of knee flexion, there was no significant difference in S1 levels and urination.
 
As in the previous [2,3], fentanyl was found to extend the knee flexion time from 78 minutes to 97 minutes (p = .0001), but did not extend to the S1 level or urinary time.
 

 
 
Procaine Penicillin Usage and Dosage: