Payment & Shipping Terms:
|Arrival Time:||4-7 Days||Appearance:||Powder|
|Usage:||For Relieve Pain||Purity:||99% Purity|
|Other Names:||Lidocaina||Export Port:||Hong Kong|
lidocaine hydrochloride oral,
lidocaine local anesthetic
Lidocaine HCL Local anesthesia Lidocaine Hydrochloride Powder for Relieve Pain 99% Purity
Molecular Weight: 234.34
vapor pressure: 4.28E-05mmHg at 25°C
Appearance: White Crystalline Powder
Water solubility of Lidocaine base: lidocaine base is almost insoluble in water.
Stability of lidocaine: Lidocaine Base is stable. It is incompatible with strong oxidants.
Lidocaine storage conditions:
Lidocaine Base should be stored in a cool dry place.
Keep the container closed when not in use.
Lidocaine also Called:
Introduction and Role of Lidocaine Base:
1.Lidocaine base is a fast-acting local anesthetic suitable for infiltration, block and topical anesthesia, Epinephrine vasoconstricts arteries, flexible bleeding and also delays the resorption of lidocaine, almost doubling the duration of anaesthesia.
2.Lidocaine base can relieve the pain of post-herpetic neuralgia (complication of herpes zoster), and can also treat temporary tinnitus. Although it can not be used as the main product of treatment, it can also play a certain therapeutic role.
3.In addition, inhaled lidocaine can also be used as a peripheral antitussive (cough suppressant) to reduce cough reflexes because it reduces the incidence of cough and any tracheal damage that may occur during anesthesia.
4.Lidocaine base and ethanol, ammonia and acetic acid have also been shown to be effective in treating jellyfish spasms, both to paralyze affected areas and to prevent further punctate cell excretion.
|Lidocaine Base Safety information||
Packing level: III
Hazard category: 6.1
Customs code: 2924299090
Dangerous goods transport code: 3249
WGK Germany: 3
Hazard Category Code: R22
Safety instructions: S22-S26-S36
RTECS number: AN7525000
Dangerous goods mark: Xn
|Specifications of Lidocaine Base||
1, aerosol: 25g (containing lidocaine 1.75g); 2, injection: each 0.2g (10ml), 0.4g (20ml).
2, injection: each 0.2g (10ml), 0.4g (20ml).
|Production method for Lidocaine Base||
1. Chloroacetyl chloride method 2,6-Dimethylaniline is chloroacetylated with chloroacetyl chloride, then condensed with diethylamine, and then acidified to form a salt to obtain lidocaine.
2. Diethylaminoacetic acid methyl ester method Condensation of 2,6-dimethylaniline with methyl N,N-diethylacetate in the presence of sodium methoxide, followed by acidification to form a salt.
The Difference Between Lidocaine Base and Lidocaine Hydrochloride
Lidocaine Base is insoluble in water and can be used as a cream and ointment.
5% ointment is applied to the mucous surface of dentistry which can be applied to the mouth.
2.5% ointment is applied to the skin for the treatment of itching.
Insoluble water Lidocaine Base can also be used as a jelly.
Adults are commonly applied to the outer wall of catheters such as esophagus, throat, trachea or urethra.
Women can use vaginal swabs with 5~7ml for topical vaginal examination.
The dosage can be up to 400mg during surgery or cystoscopy. The 24-hour prescription is limited to 600mg.
However, Lidocaine Hydrochloride is highly soluble in water and is commonly used as a medical reagent and Lidocaine Hydrochloride
Injection for direct intravenous injection, such as:
1. Make perchloric acid titration solution (0.1mol/L)
2. Making crystal violet indicator liquid
Dosage and Usage of Lidocaine Base
|Commonly Used||Injection Site||Injection Cycle|
|Adults||Once by weight 4.3mg / kg||①Intramuscular injection||
Be repeated once after 60 ~ 90 minutes.
|Adults||According to the body weight of 1mg / kg (usually 50 ~ 100mg)||②Intravenous injection||
The first load intravenous injection for 2 to 3 minutes, if necessary, every 5 minutes after repeated injections 1 or 2 times, the maximum amount within one hour does not exceed 300mg.
After the load can continue to maintain at a rate of 1 ~ 4mg per minute
|③Intravenous drip||Intravenous infusion at a rate of 0.015 ~ 0.03mg / kg per minute.|
|Older people||0.5 to 1 mg intravenous infusion per minute.||Intramuscular or intravenous injection||
Within 1 hour is 4.5 mg/kg (or 300 mg)；
The maximum maintenance is 4 mg per minute.
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