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Product Details:
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| Product Name: | IGF-1LR3 | Specification: | 1mg/vial; 0.1mg/vial |
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| Color: | White Freeze-dried Powder | Usage: | For Muscle Growth ，Fitness Use |
| Purity: | >98% | Shipment: | DHL,Fedex,EMS,UPS,HKETK |
| High Light: | human growth hormone steroid,hgh human growth hormone |
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IGF-1LR3 1MG Legal Human Growth Hormone Peptide Deliver Quality & Safely Pass Custom
Quick details
Product name: IGF-LR3 100mcg/vial
CAS NO. 946870-92-4
IGF-LR3 Dosage: 20-100 mcg per day
Storage: Refrigerator preservation
IGF-LR3 Description
IGF-LR3 usually contains 1 mg or 0.1 mg vials. It has a white powdery appearance and must be reconstituted with sterile bacteriostatic water for
injection prior to use. Similar to molecular level insulin, this peptide primarily affects bone growth, muscle growth and muscle repair.
Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and extended analog of human insulin-like growth factor .
Synthetic peptide IGF-1 LR3 is lengthened analogue of endogenous peptide hormone IGF-1 (human insulin-like growth factor 1). Unlike regular IGF-1, its prolonged version IGF-1 LR3 haves an arginine instead of a glutamic acid at the third position in its amino acid sequence (“arginine 3”), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) (“long”). Total length of its amino acid chain is 83 amino acids unlike 70 amino acids of regular IGF-1.
IGF-1 LR3 still retains its strong pharmacological activity as an agonist of the IGF-1 receptor, but due to the mentioned modifications has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs) unlike regular IGF-1 does have, and also has improved metabolic stability. As a result, it is approximately three times more potent than IGF-1, and possesses a significantly longer half-life of about 20 hours.
IGF-1 LR3 does have elimination Half-Life about 20 hours.
One study reports the median serum IGF-I level is about 370 ng/ml at the age of 18. The European Prospective Investigation into Cancer and Nutrition (EPIC) study reported an average serum IGF-1 level of 200-210 ng/ml, suggesting that this is a typical level for adults on a Western diet. Low IGF-1 levels associated with an increased risk of disease or mortality are generally about 70-80 ng/ml or lower.
UNCLEAR: Studies showed that low and high IGF-I levels are related to impaired glucose tolerance and to a higher risk of type 2 diabetes.
YES: Insulin-like growth factor 1 (IGF-1) and growth hormone (GH) interact with insulin to modulate its control of carbohydrate metabolism. New studies shows that blocking the effect of GH in the presence of low serum IGF-1 concentrations enhances insulin sensitivity.
MAY: IGF-I treatment may cause fluid and sodium retention.
YES: All milk based products, whether they’re non organic dairy products or organic milk and organic cheese, contain a certain amount of IGF-1.
The name insulin-like growth factor reflects the fact that these substances have insulin-like actions in some tissues, though they are far less potent than insulin in decreasing blood glucose concentrations.
YES: Insulin inhibits growth hormone signaling via the growth hormone receptor/JAK2/STAT5B pathway.
The hypothalamic growth hormone (GH)-releasing hormone (GHRH) promotes non-rapid eye movement sleep (NREMS). Insulin-like growth factor-1 (IGF-1) acts as a negative feedback in the somatotropic axis inhibiting GHRH and stimulating somatostatin.
There is no widely available urine test for IGF-1, but like human growth hormone, IGF-1 can be detected in blood tests.
Whey protein stimulates fasting insulin and casein stimulates circulating IGF-1. Both milk protein fractions seem to be important, but different, in the growth-stimulating effect of milk.
It is hypothesized that testosterone might induce the synthesis of IGF-1 which could affect cell proliferation.
A somatomedin C test, also called an insulin-like growth factor-1 (or IGF-1) test, helps doctors evaluate whether a person is producing a normal amount of human growth hormone (hGH, or somatotropin).
Peptide lists
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| IGF-1 LR3 | 1mg/vail | |
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