1045g/cm Toremifene Citrate Anti Estrogen Steroids CAS 89778-27-8

CAS:89778-27-8

MF:C32H36ClNO8

MW:598.08

Synonyms:(z)-4-chloro-1,2-diphenyl-1-(4-(2-(n,n-dimethylamino)ethoxy)phenyl)-1-butene ;2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-ethanamin(z)-ethanamin ;2-hydroxy-1,2,3-propanetricarboxylate(1:1) ;fareston ;fc1157a ;nk622 ;TOREMIFENE CITRATE;(z)-2-[4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy]-n,n-dimethyl-ethanamine 2-hydroxy-1,2,3-propanetricarboxylate

Melting point:160-162°C

Boiling point:146-148C

Density 1045g/cm

refractive index 1,416-1,418

storage temp. -20°C Freezer

solubility DMSO: >10mg/mL

color white to off-white

Merck 14,9550

Symbol(GHS)

Application

Toremifene citrate is an oral selective estrogen receptor modulator (SERM) derived from triphenylethylene. It is FDA approved for breast cancer treatment, and has possible medical uses for prostate cancer. Bodybuilders will use this drug to combat gynecomastia (bitch tits), but it's still very new to the scene and has some drawbacks.

It has already been covered that Toremifen is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body. As a layman explanation, Toremifen pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifen, real Estrogen cannot perform their jobs there.

Toremifen does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.

Toremifen is also agonistic to Estrogen receptors in other tissues in the body. This means that whileToremifen will act as an anti-estrogen in breast tissue and the hypothalamus, it will act as an Estrogen within the liver. This can have beneficial impacts especially during an anabolic steroid cycle, such as improving and shifting cholesterol levels into a more favorable range.


Dosage

For bodybuilding purposes, a dose of 40-60 mg/day seems to be a good starting point. If the user is trying to fight existing gynecomastia, they may choose to double the dose and add an aromatase inhibitor like Aromasin with it. For PCT, some users will kick-start with 100-120 mg/day and then lower to 40-60 mg/day for 4-6 weeks.

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