MK 677 Introduction:

MK-677 is an oral HGH SECRETAGOGUE that provides higher amplitude to the dozen or more

hgh pulses put out by the pituitary gland over the 25 hour half-life of the drug. A secretagogue is

the term for a substance that chemically signals for the pituitary gland to secrete growth

hormones. In other words, MK-677 could be compared to peptides like GHRP-6 or Ipamorelin,

only it doesn't require any injections nor does it have any side effects like GHRP-6.


This Growth Hormones Secretagogue was developed in an aim to combat such conditions as

muscle wasting, obesity and osteoporosis. It was also targeted towards treatment of elderly hip

fracture patients, so there are a myriad of studies done on safety.


Once daily use before bed at a dose of 25mg provides all of the benefits of elevated HGH and

Igf1 such as deeper sleep with more vivid dreams, improved skin, faster hair and nail growth, fat

loss, lean muscle gain, increased strength, greater nitrogen retention the the skeletal muscles,

greater protein synthesis, etc.

MK 677 Usage:

MK-677 is a medicine which acts as a potent, orally active growth hormones secretagogue,

mimicking the GH stimulating action of the endogenous hormone ghrelin. It is currently under

development as a potential treatment for reduced levels of these hormones, such as in growth

hormones deficient children or elderly adults, and human studies have shown it to increase both

muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty

in the elderly. It also alters metabolism of body fat and so may have application in the treatment of

obesity.


MK 677 Benefits:

In a study on it's effects on catabolic states, a once daily oral dose of 25mgs was given to healthy

young mensubjected to short-term diet-induced nitrogen wasting.

After 7 days of this dose, the subjects showed a sustained increase in serum concentration of

IGF-1 and Hormone; in addition, the nitrogen wasting was reversed, showing great potential for

treatment of conditions involving muscle wasting.


A study done for the treatment of osteoporosis and bone mineral density showed some increase

in bone density, so there is a true impact on bone mineral density. This can help with injury

recovery during your cycle.