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USP Anti Estrogen Steroids Treating Breast Cancer Toremifene Citrate Powder

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USP Anti Estrogen Steroids Treating Breast Cancer Toremifene Citrate Powder

USP Anti Estrogen Steroids Treating Breast Cancer Toremifene Citrate Powder
USP Anti Estrogen Steroids Treating Breast Cancer Toremifene Citrate Powder USP Anti Estrogen Steroids Treating Breast Cancer Toremifene Citrate Powder

Large Image :  USP Anti Estrogen Steroids Treating Breast Cancer Toremifene Citrate Powder Get Best Price

Product Details:
Place of Origin: China (whatsapp+8615711952876)
Brand Name: RAWSGEAR
Certification: ISO9001, KOSHER, GMP, SGS
Model Number: 89778-27-8
Payment & Shipping Terms:
Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: Foil bag
Delivery Time: 3-5 work days
Payment Terms: Western Union, MoneyGram, T/T, bitcoin
Supply Ability: Mass in stock
Detailed Product Description
Product Name: Toremifene Apperance: White Powder
Quality Stand: USP Lead Time: 3-7 Days
High Light:

Treating Breast Cancer Anti Estrogen Steroids

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Toremifene Citrate Anti Estrogen Steroids

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USP Toremifene Citrate Powder

 

China Treating Breast Cancer Toremifene Anti Estrogen Steroids Toremifene Citrate Powder Bodybuilding Use

 

 

Quick details:

 

Product Name:Toremifene citrate
CAS: 89778-27-8
Molecular Formula: C32H36ClNO8
Molecular Weight: 598.09
Melting Point: 158-164 ºC
Appearance: White or almost white powder
Purity:99%
We supply SARMS, Steroids powder, Nootropic, Sex powder, Weight loss raw powder, Anti-cancer raw powder, Painkiller raw powder, lyophilized peptide, etc.

 

 

Description:

 

Toremifene citrate is an anti-estrogenic drug, specifically classified as a Selective Estrogen-Receptor
Modulator (SERM) with mixed agonist and antagonist properties.Toremifene citrate is a non-steroidal triphenylethylene derivative, similar in structure and action to both Nolvadex (tamoxifen citrate) and Clomid (clomiphene citrate).

Toremifene citrate is used for the treatment of breast cancer in postmenopausal women with estrogen-receptor positive or estrogen unknown (unsure if the cancer is estrogen responsive) tumors. Toremifene citrate works by attaching to the estrogen receptor in various tissues in a competitive manner, blocking endogenous estrogen from exerting biological activity. As an anti-estrogen in many tissues, male bodybuilders and athletes may use toremifene citrate to counter some of the side effects associated with the use of aromatizable or estrogenic anabolic/androgenic steroids. This may include gynocomastia, body fat gain, and increased water retention

Toremifene citrate for steroid users is its ability to increase the production of luteinizing hormone and follicle stimulating hormone, and therefore increasing testosterone. This ability is why it is often used by steroid users during their post-cycle therapy. Toremifene citrate would accomplish this by blocking the negative feedback inhibition caused by estrogen at the hypothalamus and pituitary, and this in turn will help to increase the production of these hormones.

 

 

Application:

 

Toremifene citrate is a trivalent selective estrogen receptor modulator (SERM). It is FDA approved for the treatment of breast cancer and may be used for the treatment of prostate cancer. Bodybuilders use this drug to combat gynecological problems (cancer teeth), but it is still on the scene. Very new and has some flaws.

 

Toremifene is a SERM that works by blocking estrogen in certain tissues of the body. As an explanation, Toremifene acts as a "fake" estrogen that occupies the estrogen receptors in the breast tissue. Toremifene occupies these receptors and the real estrogen cannot do its job there.

Toremifene does not lower plasma levels of estrogen. In addition to antagonizing estrogen receptors in breast tissue, it also antagonizes estrogen in the hypothalamus, essentially "tricking" the hypothalamus into thinking there is little or no estrogen in the body and increasing its production.

Testosterone uses aromatase to restore these levels.

 

Toremifene is also painful for estrogen receptors in other tissues of the body. Thus, toremifene acts as an anti-estrogen in breast tissue and lipids in the blood, but it acts as an estrogen in the liver. Especially during anabolic steroid cycles, it has beneficial effects such as improving cholesterol levels and moving them into more favorable ranges.

 

USP Anti Estrogen Steroids Treating Breast Cancer Toremifene Citrate Powder 0

 

 

Does toremifene citrate interact with other drugs you are taking?


Products that may interact with Toremifene Citrate Powder include blood thinner (such as warfarin), estrogen, tibolone, and drugs that affect liver enzymes (including some antiepileptic drugs, such as carbamazepine/clonazepam/phenobarbital/phenytoin), rifampicin).

In addition to this product, many drugs may affect the heart rhythm (QT prolongation), including amiodarone, granisetron, pimozide, procainamide, quinidine, sotalol, and macrolide antibiotics (such as erythromycin).

 

Drugs that reduce renal calcium excretion, such as thiazide diuretics, can increase hypercalcemia. Enzyme inducers such as phenytoin sodium, phenobarbital, and carbamazepine can accelerate the excretion of toremifene and reduce the steady-state serum concentration. In this case, you need to adjust the amount of your product. It has been confirmed that the anti-estrogen drugs of this product have a synergistic effect with the anticoagulant drugs of sharing, resulting in a serious increase in bleeding time. Therefore, it should be avoided to take these drugs at the same time. Theoretically, the main metabolic pathway of toremifene is the CYP3A enzyme system. Drugs that inhibit the enzyme system, such as ketoconazole and similar antifungal drugs, erythromycin, and Triacetyloleandomycin can inhibit the metabolism of toremifene. Therefore, careful consideration should be given to the simultaneous application of such drugs.

 

 

Toremifene Citrate use/dosing:


Toremifene citrate is interchangeable with tamoxifen citrate (Nolvadex) while on cycle or in post-cycle therapy. 20mg of tamoxifen citrate = 60mg of toremifene citrate3 . From this Toremifene citrate can be extrapolated that for treatment and/or prevention of gynocomastia sixty milligrams should be sufficient for treatment. The recommended dosage for breast cancer treatment is one 60mg tablet administered once per day. During steroid treatment athletes and bodybuilders may use 30mg to 60mg per day

For use during post-cycle therapy users have anecdotally indicated that doses ranging between 60 and 120 mgs per day are average. Most users have reported when using Toremifene citrate for their post- cycle therapy they will administer the drug for a minimum of three weeks. A maximum length has not necessarily been established due to the few side effects associated with the compound. In this case, this compound can be run for as long as wanted with little to no concern being needed to be paid to potential side effects. See the below section for more details.

Female athletes occasionally use clomiphene citrate for the reduction of estrogenicity near the time of a bodybuilding contest. In some instances this may aid in increasing fat loss and muscularity, particularly in female trouble areas such as the hips and thighs. The drug, however, often produces very troubling side effects in pre-menopausal women, and is likewise not in very high demand among this group.

 

 

Drug interactions

 

1. Toremifene Citrate will reduce the renal excretion of calcium drugs, such as thiazide drugs, is the risk of increased hypercalcemia.

2. Enzyme inducers such as phenobarbital, phenytoin sodium and carbamazepine can increase the metabolic rate of this product and decrease its concentration when it reaches steady state in serum. In this case, the daily dose of this product should be doubled.

3. It is known that the combination of anti-estrogen drugs and warfarin anticoagulants together with Toremifene Citrate might lead to prolonged bleeding time. So Toremifene Citrate should be avoided in combination with the above drugs.

Pharmacokinetics:

Absorption: the absorption of Toremifene Citrate is rapid after oral administration, and the serum concentration reaches the peak at about 3 hours (2-5 hours) after administration.

Metabolism: This product can be widely metabolized in human body by cytochrome P450 dependent multifunctional liver oxidase.

Excretion: Toremifene Citrate is mainly eliminated by feces in the form of metabolites, and the hepatic and intestinal circulation can be observed

Serum protein binding rate: the product mainly binds to albumin, and the serum protein binding rate is more than 99.5%.

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